Table 1 Characteristics of patients, oxygenation and surgical data
Variable | Controls | Hyperoxia pretreated | p-value |
|---|---|---|---|
(n = 19) | (n = 20) | ||
Age (years) | 65 (8) | 66 (11) | 0.89 |
Gender (male/female) | 15/5 | 14/5 | 0.67 |
Preoperative medications | |||
Ca-channel blockers, n (%) | 6 (31.5) | 1 (5) | 0.01 |
Nitrates, n (%) | 12 (63) | 8 (40) | 0.13 |
β-blockers, n (%) | 17 (89) | 14 (70) | 0.13 |
ACE-inhibitors, n (%) | 14 (74) | 10 (50) | 0.11 |
Statins, n (%) | 15 (79) | 11 (55) | 0.27 |
Preoperative ejection fraction (%) | 58 (11) | 53 (11) | 0.16 |
paO2 10 min after intubation (mmHg) | 130 (49) | 402 (68) | <0.001 |
paO2 60 min after intubation (mmHg) | 108 (27) | 369 (75) | <0.001 |
Cross-clamping time (min) | 47 (33) | 46 (30) | 0.89 |
Duration of cardiopulmonary bypass (min) | 68 (36) | 63 (27) | 0.66 |
Number of vessels bypassed | 3.3 (0.8) | 3.5 (0.8) | 0.50 |
Need for inotropic support, n (%) | 7 (37) | 6 (30) | 0.80 |