No effect of 6-month intake of glucosamine sulfate on Modic changes or high intensity zones in the lumbar spine: sub-group analysis of a randomized controlled trial

Table 1 Frequency of Modic changes (MC) in total sub-sample and by treatment group (glucosamine or placebo)

Total sub-sample (45 patients, 450 lumbar endplates)
		Pre-treatment
Post-treatment		No MC	MC I	MC I/II	MC I/III	MC II	MC II/I	MC II/III	MC III	MC III/I	MC III/II
	Total	309	26	17	2	76	11	4	2	1	2
No MC	299	299	0	0	0	0	0	0	0	0	0
MC I	25	7	16	0	0	1	0	0	0	1	0
MC I/II	27	3	7	13	0	2	2	0	0	0	0
MC I/III	1	0	0	0	1	0	0	0	0	0	0
MC II	71	0	0	1	0	69	1	0	0	0	0
MC II/I	20	0	3	3	1	4	8	1	0	0	0
MC II/III	3	0	0	0	0	0	0	3	0	0	0
MC III	0	0	0	0	0	0	0	0	0	0	0
MC III/I	0	0	0	0	0	0	0	0	0	0	0
MC III/II	4	0	0	0	0	0	0	0	2	0	2
Glucosamine group (19 patients, 190 lumbar endplates)
		Pre-treatment
Post-treatment		No MC	MC I	MC I/II	MC I/III	MC II	MC II/I	MC II/III	MC III	MC III/I	MC III/II
	Total	126	18	8	2	28	5	1	2	0	0
No MC	121	121	0	0	0	0	0	0	0	0	0
MC I	15	3	12	0	0	0	0	0	0	0	0
MC I/II	15	2	4	7	0	1	1	0	0	0	0
MC I/III	1	0	0	0	1	0	0	0	0	0	0
MC II	28	0	0	1	0	26	1	0	0	0	0
MC II/I	7	0	2	0	1	1	3	0	0	0	0
MC II/III	1	0	0	0	0	0	0	1	0	0	0
MC III	0	0	0	0	0	0	0	0	0	0	0
MC III/I	0	0	0	0	0	0	0	0	0	0	0
MC III/II	2	0	0	0	0	0	0	0	2	0	0
Placebo group (26 patients, 260 lumbar endplates)
		Pre-treatment
Post-treatment		No MC	MC I	MC I/II	MC I/III	MC II	MC II/I	MC II/III	MC III	MC III/I	MC III/II
	Total	183	8	9	0	48	6	3	0	1	2
No MC	178	178	0	0	0	0	0	0	0	0	0
MC I	10	4	4	0	0	1	0	0	0	1	0
MC I/II	12	1	3	6	0	1	1	0	0	0	0
MC I/III	0	0	0	0	0	0	0	0	0	0	0
MC II	43	0	0	0	0	43	0	0	0	0	0
MC II/I	13	0	1	3	0	3	5	1	0	0	0
MC II/III	2	0	0	0	0	0	0	2	0	0	0
MC III	0	0	0	0	0	0	0	0	0	0	0
MC III/I	0	0	0	0	0	0	0	0	0	0	0
MC III/II	2	0	0	0	0	0	0	0	0	0	2

ISSN: 1477-5751