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Table 2 Distribution of genotype and allele frequencies for the CTGF promoter polymorphism at -945

From: The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes

 

Genotype frequencies (%)

Total

P-value

CTGF -945GC polymorphism

Diabetic Nephropathy

Normoalbuminuria

  

CC

126 (28.1)

126 (30.1)

252 (29.0)

0.481

CG

220 (49.1)

201 (48.0)

421 (48.6)

 

GG

102 (22.8)

92 (21.9)

194 (22.4)

 

Total

448 (100)

448 (100)

867 (100)

 
 

Allele frequencies (%)

Odds ratio

P-value

CTGF -945 promoter polymorphism

Diabetic Nephropathy

Normoalbuminuria

  

Allele C

472 (52.7)

453 (54.0)

1.057

0.596

Allele G

424 (47.3)

385 (46.0)

  
  1. P-values were calculated using Fisher's exact test and Chi-square analysis respectively. There is no difference in genotype or allele frequencies between diabetic nephropathy patients and normoalbuminuric patients at baseline.